Inseal Medical Ltd. develops and manufactures percutaneous vascular closure devices for sealing of puncture sites following treatment involving a large bore sheath. The Company’s first product is the InSeal intravascular closure device, which supports the closure of 14-21Fr punctures in vessels of 6-10mm in diameter.

InSeal Medical Ltd. is a fully owned subsidiary of E-Pacing Inc. with offices in Caesarea Industrial Park, Israel. The Company is backed by Polaris Venture Partners (Waltham, MA).


Avi Penner

PhD., Founder & CEO

Avi serves as the company CEO & CTO. Prior to founding InSeal Medical Ltd. and its parent company E-Pacing Inc., Avi worked for nine years as the Vice President of R&D at Remon Medical Technologies, which was acquired by Boston Scientific. Prior to Remon, Avi was at Medtronic InStent, where he led projects for the development of coronary and peripheral stent systems.

Avi holds a Bsc. in Chemistry (with Honors) and a PhD. in Physical Chemistry (with Distinction), both from the Tel-Aviv University. Avi is the principal or co-inventor of more than 50 patents and patent applications relating to medical devices.


Alon Ben-Yosef

Vice President Development

Prior to InSeal Medical Ltd., Alon was employed for 9 years as the Head of Engineering group at Remon Medical Technologies, responsible for implant development. Prior to Remon, Alon served as the project manager of coronary and peripheral stents and delivery systems at Medtronic InStent for two years.

Alon holds a B.Sc. in Mechanical Engineering from the Technion, Israel (1997).

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